Abstract

SOLIS, Aida et al. Enzymatic Hydrolysis of N-protected 2-Hydroxymethylpiperidine Acetates. J. Mex. Chem. Soc [online]. 2008, vol.52, n.3, pp.181-184. ISSN 1870-249X.

Liver acetone powders (LAPs) were used as hydrolase sources to biocatalyze the hydrolysis of N-protected-2-hydroxymethylpiperidine acetates (N-Ts and N-Boc). Different reaction conditions were evaluated, like source of LAP (cat, guinea pig, chicken, dog, sheep, bovine, rat, mouse, pig and rabbit), proportion of cosolvent, type of cosolvent and pH.

Keywords : Liver acetone powder; 2-hydroxymethylpiperidine; bio-catalysis; hydrolysis.

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