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Revista de la Facultad de Medicina (México)

On-line version ISSN 2448-4865Print version ISSN 0026-1742


GONZALEZ-VILLALVA, Adriana et al. The megakaryocyte: a very original cell. Rev. Fac. Med. (Méx.) [online]. 2019, vol.62, n.1, pp.6-18. ISSN 2448-4865.

The Megakaryocyte is the biggest cell in the bone marrow; therefore, it is easy to recognize in a bone marrow aspirate. In humans, this cell differs from others because of its size, its polyploidy and because it grows by endomitosis. It is the only human cell that grows this way. In addition, the megakaryocyte has very important biological functions. Its best-known function is being in charge of the production of platelets, which are essential for hemostasis, the repair of damaged blood vessels, and healing the tissues surrounding wounds. However, in recent years, other functions have been attributed to the megakaryocyte, which will be discussed in this review.

Keywords : Megakaryocyte; platelet; hemostasis; haematopoietic stem cell (THC); fibrosis.

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