Abstract

CASTILLO RAMIREZ, Rogelio Edgar et al. Rapidly progressive renal injury as a manifestation of acute tubular necrosis with an uncertain origin in a marathonist: A differential diagnosis is not always simple. Rev. Fac. Med. (Méx.) [online]. 2017, vol.60, n.6, pp.19-25. ISSN 2448-4865.

The rapidly progressive renal failure syndrome corresponds to an acute kidney injury that causes an accelerated decrease of the glomerular filtration rate in hours to days or weeks. After pre-renal causes were dismissed, a differential diagnosis with glomerularcauses, vascularcauses (thrombosis), obstructive causes, interstitial nephritis and acute tubular necrosis must be established. We describe the case of a rapidly progressive decline of the renal function that was managed with intravenous steroids and freshly frozen plasma due to the diagnostic probability of thrombotic microangiopathy, interstitial nephritis and rapidly progressive glomerulonephritis. Subseguently, an acute tubular necrosis was confirmed by a renal biopsy without any previous clinical evidence suggesting a clear presence or etiology of this entity.

Keywords : Renal injury; tubular necrosis; steroids.

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