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Revista mexicana de oftalmología
On-line version ISSN 2604-1227Print version ISSN 0187-4519
Abstract
CARDOZO-LOVERA, María A. et al. Preoperative neutrophil-to-lymphocyte ratio in patients treated with penetrating keratoplasty as a predictor of corneal rejection. Rev. mex. oftalmol [online]. 2022, vol.96, n.3, pp.118-122. Epub Oct 07, 2022. ISSN 2604-1227. https://doi.org/10.24875/rmo.m22000226.
Purpose:
To determine the utility of the neutrophil-to-lymphocyte ratio as a predictor of rejection in patients treated with penetrating keratoplasty
Methods:
Retrospective, observational, analytical study. The Kruskal-Wallis test, chi-square test, ROC curve, and area under the curve were used.
Results:
A total of 111 out of the156 patients included did not show rejection (Group A) while 45 did show endothelial rejection (Group B). Keratoconus was present in 47.74% (group A) and bullous pseudophakic keratopathy (group B) in 35.55% (p = 0.029). The mean time to present rejection was 9 ± 7 months. The greatest risk factor was glaucoma (26.66%). The mean neutrophil-to-lymphocyte ratio of group A was 1.94 ± 0.67, and of group B, 2.49 ± 1.46 (p = 0.032) The ratio cut-off value to present rejection was 2.04.
Conclusion:
The mean preoperative visual acuity in both groups was similar while the postoperative visual capacity in group A was lower. Glaucoma was the greatest risk factor. There was a significant difference in the ratio of group B. The ratio cut-off value to predict corneal rejection was significant (≥ 2.04).
Keywords : Rejection; Keratoplasty; Lymphocyte; Neutrophil; Ratio; Corneal tansplantation.
