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Gaceta mexicana de oncología
On-line version ISSN 2565-005XPrint version ISSN 1665-9201
Abstract
PALENCIA-PALACIOS, Maribel; ROMERO-ROJAS, Alfredo E.; PARRA-MEDINA, Rafael and LOPEZ-CORREA, Patricia. Alveolar rhabdomyosarcoma with aberrant expression of epithelial and neuroendocrine epithelial and neuroendocrine biomarkers. Gac. mex. oncol. [online]. 2023, vol.22, suppl.1, pp.74-79. Epub Sep 11, 2023. ISSN 2565-005X. https://doi.org/10.24875/j.gamo.22000104.
Background:
Alveolar rhabdomyosarcoma (ARMSa) is a sarcoma with skeletal muscle differentiation, which occurs more frequently in adolescents and young adults, and is considered to have a poor prognosis. The most frequent location is the extremities.
Case description:
A 78-year-old woman presented with a heterogeneous mass in the left thigh of 8 months of evolution, reaching a size of 11 cm in diameter, with vascular involvement. Biopsy showed an ARMSa with aberrant expression of epithelial and neuroendocrine markers.
Conclusions:
In the category of ARMSa it is important to know the immunophenotype that characterizes them, as well as the aberrant expression of epithelial and neuroendocrine markers.
Keywords : Alveolar rhabdomyosarcoma; Epithelial; Synaptophysin; Chromogranin; Immunohistochemistry.
