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Revista alergia México
On-line version ISSN 2448-9190
Abstract
BARRIOS-DIAZ, Britza et al. ABCD-10 scale as a predict of mortality in children with severe pharmacodermias. Case report. Rev. alerg. Méx. [online]. 2023, vol.70, n.1, pp.43-46. Epub Aug 25, 2023. ISSN 2448-9190. https://doi.org/10.29262/ram.v70i1.1069.
Background:
The severe pharmacodermias (SF) are associated with high morbidity and mortality. Chronic kidney failure (CKD) related with dialysis is one of the main factors associated with higher mortality. ABCD-10 is a predictive mortality scale that includes the history of dialysis.
Case report:
Male 2 years old with a history of CKD on peritoneal dialysis and Lennox-Gastaut syndrome, admitted to the hospital due to acute peritonitis and developed SJS-NET secondary to phenytoin administration. He was treated with immunoglobulin and systemic steroid without improvement. Septic shock was added, presenting a fatal outcome.
Conclusions:
In the case presented, the ABCD-10 scale was applied, reporting a greater prediction of mortality compared to SCORTEN due to a history of dialysis. In children with SF there are no validated predictive mortality. Future initiatives should search for risk factors for mortality in children who develop SF for the creation of a predictive mortality scale.
Keywords : Stevens-Johnson syndrome; Toxic epidermic necrolysis; Dialysis; Mortality; ABCD-10 scale; Children.
