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Revista alergia México
On-line version ISSN 2448-9190
Abstract
CAMARGO-VARGAS, Bethy et al. Food protein-induced enterocolitis syndrome in a patient with pseudo-Bartter syndrome associated with cystic fibrosis. A case report. Rev. alerg. Méx. [online]. 2021, vol.68, n.4, pp.300-303. Epub Apr 08, 2022. ISSN 2448-9190. https://doi.org/10.29262/ram.v68i4.974.
Introduction:
Food protein-induced enterocolitis is a non-immunoglobulin E-mediated food allergy with acute manifestations like recurrent vomiting, dehydration, and shock. It is a rare pathology that requires a high index of suspicion. Pseudo-Bartter syndrome (metabolic alkalosis, hypokalemia and hypochloremia in the absence of tubulopathy) is an infrequent complication of cystic fibrosis.
Case report:
A 5-month-old boy with recurrent vomiting, dehydration, and shock; who had been breastfed and had consumed baby formula three hours prior to the onset of symptoms. Laboratory tests confirmed hyponatremia, hypochloremic metabolic alkalosis, and hypokalemia in absence of tubulopathy; two iontophoresis showed altered results, stool elastase was decreased, and genetic sequencing confirmed the diagnosis of cystic fibrosis. The provocation test confirmed food protein-induced enterocolitis syndrome.
Conclusion:
Recurrent vomiting and dehydration after the intake of milk formula must lead to suspicion of food protein-induced enterocolitis syndrome. If pseudo-Bartter syndrome is found, cystic fibrosis must be ruled out.
Keywords : Food protein-induced enterocolitis syndrome; Pseudo-Bartter syndrome; Food allergy; Cystic fibrosis.