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Revista alergia México

On-line version ISSN 2448-9190

Abstract

RINCON-PEREZ, Catalina et al. Clinical characteristics of a population with atopic dermatitis in a tertiary center. Rev. alerg. Méx. [online]. 2021, vol.68, n.1, pp.12-25.  Epub Aug 30, 2021. ISSN 2448-9190.  https://doi.org/10.29262/ram.v68i1.843.

Background:

Information about the clinical and epidemiological characteristics of atopic dermatitis (AD) is essential to generate knowledge of the disease and its socioeconomic impact.

Objective:

To describe the clinical characteristics of the patients of an atopic dermatitis clinic.

Methods:

An observational, retrospective, and cross-sectional study. Demographic data, severity of the AD (according to the Eczema Area Severity Index), clinical phenotype, total serum IgE, the presence of allergic and non-allergic comorbidities, as well as of anxiety and depression, were recorded by means of targeted questionnaire and Hamilton Scale. Descriptive and inferential statistics were obtained, considering a statistical significance associated with a value of p <0.05.

Results:

187 patients were included; the median age was 12 years with a range of 1-87 years. Differences were found regarding sex and severity (p < 0.05). Mild forms of AD were presented in 57.8% of the patients, moderate forms in 20.9%, and severe forms in 21.4%. The severity was associated with allergic comorbidities such as asthma (p = 0.001) and allergic conjunctivitis (p <0.001). Severe AD was associated with a state of anxiety and depression (p <0.05), as well as with ocular affectation (p<0.001).

Conclusion:

The pediatric population is the most affected by AD; however, in the adult population, the severe form associated with allergic comorbidities is observed.

Keywords : Atopic dermatitis; Classification; Comorbidities; Phenotype.

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