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Revista alergia México
On-line version ISSN 2448-9190
Abstract
GONZALEZ-DIAZ, Sandra Nora et al. Evaluation of vitamin D serum levels in asthmatic adults and their relationship with asthma control. Rev. alerg. Méx. [online]. 2018, vol.65, n.4, pp.362-371. ISSN 2448-9190. https://doi.org/10.29262/ram.v65i4.386.
Background:
Decreased levels of vitamin D influence on the control and severity of asthma.
Objective:
To evaluate the relationship between vitamin D serum levels and asthma control, as well as nutritional status, quality of life and patient comorbidities.
Methods:
Cross-sectional, observational, descriptive study of 43 asthmatic patients older than 18 years of age. Multiple logistic and multiple linear regression multivariate analyses of variance were performed; a p-value ≤ 0.05 was considered to be statistically significant.
Results:
Insufficient vitamin D levels were determined in 83.7 % of patients; 93 % had at least one asthma exacerbation in the previous year. There was no relationship between vitamin D serum levels and asthma control as measured by ACT and FEV1. There was a significant association between body mass index and vitamin D levels (p = 0.013). With a quality of life questionnaire for asthmatic adults, 76.7 % were recorded to have a poor quality of life.
Conclusions:
No relationship was observed between vitamin D serum levels and asthma control in the patients. Most patients had insufficient vitamin D serum levels, uncontrolled asthma, and poor quality of life. Overweight and grade I obesity were associated with vitamin D insufficient levels.
Keywords : Asthma; Vitamin D; Asthma control test; Quality of life; Body mass index.