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Medicina crítica (Colegio Mexicano de Medicina Crítica)
Print version ISSN 2448-8909
Abstract
MENDOZA CHAVEZ, Rocío; MENDOZA RODRIGUEZ, Martín; LOPEZ GONZALEZ, Alfonso and CORTES MUNGUIA, José Alfredo. Epidemiological aspects of the syndrome of immunosuppression, inflammation and persistent catabolism in critical chronic ill patients. Med. crít. (Col. Mex. Med. Crít.) [online]. 2019, vol.33, n.1, pp.21-25. Epub Dec 04, 2020. ISSN 2448-8909.
Critically ill chronic patients maintain a persistent inflammatory environment, reduced immunity and progressive consumption of physiological reserves. They are characterized by hospital admissions with longer stays, higher mortality and costs.
General objective: To describe the characteristics of the syndrome of inflammation, immunosuppression and persistent catabolism in critically ill critically ill patients hospitalized in the Intensive Care Unit of the La Villa General Hospital. In order to know the epidemiological aspects.
Material and methods:
Prospective, descriptive and observational clinical, analytical study. Patients were admitted with PICS criteria according to the NUTRIC score and clinical features from January-April 2018. Descriptive statistics tests were performed for qualitative variables, quantitative measures were used for quantitative central. Inferential tests to compare qualitative variables and for quantitative 2 x 2 tables for calculating the odds ratio.
Results:
25 patients met criteria of PICS, incidence of 37.9%, the distribution by sex was 60% men and 40% women. Average age was 48.8. The most common diagnoses hypovolemic shock (28%), septic shock (16%), 68% of patients had a low nutritional risk and 32% high risk, 84% of patients required some kind of support the most common was ventilation mechanical, the most common complications were infectious (80%) mainly VAP. The mortality was 20%.
Conclusions:
The results in this study do not differ from those reported in the literature at the international level, the syndrome of PICS is presented in patients with older age, longer hospital stay and higher nutritional deficiencies in which biological reserves are not sufficient to avoid immunosuppression that leads to and generates the vicious circle that ultimately leads to death not only within the ICU.
Keywords : Syndrome of inflammation; immunosuppression and persistent catabolism; critically ill chronically ill patients; Intensive Care Unit.
