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Anestesia en México

On-line version ISSN 2448-8771Print version ISSN 1405-0056

Abstract

JIMENEZ CARDONA, Maria Beatriz. Intrathecal administration in minimal dose of morphine for postoperative pain management in caesarean section. Anest. Méx. [online]. 2018, vol.30, n.3, pp.38-46. ISSN 2448-8771.

Intrathecal morphine has been used, with good results in the treatment of acute pain. Multiple doses have been used, trying to find the optimal dose.

Objective:

To know the optimum dosage of morphine for postoperative analgesia in patients operated of Caesarea, with minimal side effects.

Material and method:

we designed randomized and controlled clinical, prospective trial. We included 100 patients of Cesarean section for postoperative pain control, ASA I and II. The one group of 50 patients, received intrathecal morphine 80 μg, more 9 mg, 0.5% hyperbaric bupivacaine. Group two, of 50 patients, received the same but with 40 μg of morphine. They quantified the incidence of pain by EVA, nausea, vomiting and pruritus, during the next postoperative 24 hours. The value of (P < 0.05) was determined.

Results:

Analgesia was effective in both groups. The itching was the most frequent symptom and is directly related to the used dose.

Conclusion:

Postoperative analgesia with spinal morphine, is the “Gould standard” for acute pain. Low doses are better in order to avoid serious side effects. It is best not to use morphine postoperative monotherapy, the best scheme is multimodal analgesia and doses of rescue.

Keywords : Morphine intratecal; postoperative pain; cesarean section.

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