Abstract

MORALES-UBALDO, Ana et al. Antibacterial activity of the Croton draco hidroalcoholic extract on bacteria of sanitary importance. Abanico vet [online]. 2020, vol.10, e1.  Epub June 30, 2020. ISSN 2448-6132.  https://doi.org/10.21929/abavet2020.2.

The World Organization for Animal Health (OIE) mentions that the inappropriate use of antibiotics has led to the emergence of strains of resistant bacteria to the mechanisms of action of these drugs, due to the scarcity of effective therapies, the development of new treatment options is required for diseases that affect health, in this respect plant extracts or their pure compounds offer an alternative. The aim of the present investigation was to characterize and evaluate the in vitro antibacterial activity of the hydroalcoholic extract of Croton draco on bacteria of sanitary importance. The extract was obtained by hydroalcoholic maceration, a qualitative and chemical characterization of the extract was carried out, and the antibacterial activity was determined by the Minimum Inhibitory Concentration (MIC) and the Minimum Bactericidal Concentration (MBC). The qualitative characterization tests performed on the hydroalcoholic extract of Croton draco indicate the presence of phenolic compounds, terpenes, saponins and alkaloids, by gas chromatography the presence of thymol and carvacrol was determined in concentrations of 0.5340 mg/ml and 0.4206 mg/mL respectively. The bacteria showed different degrees of sensitivity to the hydroalcoholic extract, however, greater activity was determined against Gram positive bacteria such as Listeria monocytogenes, Staphylococcus aureus and Bacillus subtilis.

Keywords : Croton draco; Hydroalcoholic extract; Antibacterial; Minimum Inhibitory Concentration; Minimum Bactericidal Concentration.

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