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Mundo nano. Revista interdisciplinaria en nanociencias y nanotecnología
On-line version ISSN 2448-5691Print version ISSN 2007-5979
Abstract
CLAUDIO-RIZO, Jesús A.; CANO SALAZAR, Lucia F.; FLORES-GUIA, Tirso E. and CABRERA-MUNGUIA, Denis A.. Nanostructured metal-organic frameworks (MOFs) applied to controlled drug delivery. Mundo nano [online]. 2021, vol.14, n.26, 00008. Epub Mar 03, 2021. ISSN 2448-5691. https://doi.org/10.22201/ceiich.24485691e.2021.26.69634.
Metal-organics frameworks are coordination polymers constituted of a metallic center and an organic ligand that can be designed using biocompatible metal ions (e.g. Fe+3, Zn+2, Mg+2, Ca+2 y Mo+6) and bioactive organic ligands yielding to the modulation of the structure and properties materials in the nano scale. The aim of this work is provide an outlook about the materials applied for drug delivery systems, emphasizing the advantages, advances and challenges in the controlled drug delivery using nanostructured MOFs, the delivery mechanism, degradability and antimicrobial activity is also presented.
Keywords : MOFs; nanostructure; controlled drug delivery; biocompatibility.