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Revista biomédica

On-line version ISSN 2007-8447Print version ISSN 0188-493X

Abstract

CARDONA-SOSA, Maribel Patricia; ESTRELLA-CASTILLO, Damaris Francis  and  RUBIO-ZAPATA, Héctor Armando. Excess weight and malignancy of breast tumors in Yucatan women. Rev. biomédica [online]. 2018, vol.29, n.1, pp.5-11. ISSN 2007-8447.  https://doi.org/10.32776/revbiomed.v29i1.584.

Introduction

Obesity, overweight and carcinogenesis are of multifactorial origin and result of chronic processes where the environment and genetics play a fundamental role. So its magnitude has regional, national and international variations. In Yucatan the prevalence of obesity is very high, so that its implication in cancer could be higher than in other populations.

Material and methods

Case-control study, Probabilistic sample of 400 women aged 20 to 65 attended at the ISSSTE regional hospital in Merida, Yucatan in 2013-2014; The cases: 200 women with histopathological diagnosis of breast tumor and controls: 200 women without mastopathy, matched by age. Excess weight BMI> 25. Chi2, ANOVA, t-Student and difference in proportions.

Results

64% of the mammary tumors were of the malignant type and 36% of the benign type. 91.5% of women with malignant tumors, 65% of women with benign tumors, and 59% of women without breast tumors were overweight or obesity. Excess weight was associated with malignant tumors, OR 5.65 (95% CI 2.57-12.4, p <0.001). The most prevalent neoplasms were ductal (65%) and lobular (19%) carcinomas.

Conclusions

Excess weight is associated with the presence of breast tumors especially of malignant type in Yucatecan women, so that weight control in women with risk factors for breast cancer may be a preventive factor for the process of carcinogenesis.

Keywords : cancer; breast; risk obesity; overweight.

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