Clinical cases:

We present two cases of Bellini’s Collecting Duct Renal Carcinoma (CDRC) that appear as suspicious kidney masses with enhancement of the urotelium, without a determinant radiological appearance, diagnosed by anatomo-pathological analysis. We revise the medical history, histological findings and make a review of the literature.

Importance / Clinical implication:

Bellini’s collecting duct renal carcinoma is a very rare and aggressive type of kidney cancer (less than 1%), usually diagnosed at advanced stages. It does not present specific radiological characteristics, which makes necessary the histologic and inmunohistochemical analysis to confirm the diagnosis. We must suspect CDRC in infiltrative medular renal masses that do not affect kidney shape, and treat as soon as possible performing surgery, whenever feasible, normally associated with adjuvant chemotherapy. Nevertheless, it usually has an unfavourable evolution.

Conclusion:

It is imperative to diagnose and treat this kind of tumours as soon as possible due to its aggressiveness and fatal prognosis.

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