Abstract

GARCIA CANO RUBI, Nancy Paulina et al. Evaluation of sow seroconversion with the use of inoculum at different doses and vehicles against porcine epidemic diarrhea. Rev. mex. de cienc. pecuarias [online]. 2023, vol.14, n.2, pp.466-475.  Epub June 26, 2023. ISSN 2448-6698.  https://doi.org/10.22319/rmcp.v14i2.6146.

Porcine epidemic diarrhea (PED) is a highly contagious enteric disease of pigs, which has caused great economic losses to the swine industry worldwide. The known measure for PED control prior to the development and launch of vaccines in 2017 in Mexico, was "feedback" or "liquefaction". It was a widely used measure during the PED outbreak in 2013; however, there is no homogeneity in its use among the various authors who recommend it. Currently, several studies have experimented with other types of prophylaxis, such as oral immunization with PED virus obtained from cell culture isolation, which allows quantification of the infectious virus and ensures that only the virus, and no other agent, is being used as inoculum. The objective of the present study was to compare the time of seroconversion in sows inoculated with the quantified virus with four different vehicles (milk, wheat, direct, and water) and different doses of vehicle (1 ml, 2 ml, and 3 ml) at different pregnancy stages and with a different number of farrowings. The study was conducted at CEIEPP, a full-cycle farm with 170 females. The present study showed that the vehicles with the best results were the inoculum with water and the direct inoculum combined with the 1 ml dose, as the combination of these vehicles and an inoculum dose resulted in seroconversion in more than 90 % of the sows from the second week post inoculation.

Keywords : Inoculum; Porcine Epidemic Diarrhea; Seroconversion.

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