Abstract

PENA-TORRES, Edgar Fernando et al. Hydroxycinnamic acids in animal production: pharmacokinetics, pharmacodynamics and growth promoting effects. Review. Rev. mex. de cienc. pecuarias [online]. 2019, vol.10, n.2, pp.391-415. ISSN 2448-6698.  https://doi.org/10.22319/rmcp.v10i2.4526.

Use of natural source additives in animal production is increasingly important because they potentially promote growth in ways similar to synthetic compounds, such as anabolic hormones and antibiotics, but without risks to animal or consumer health or degrading meat quality. Encompassing a wide variety of compounds extracted from different plant parts, natural origin additives can be administered as essential oils, mixtures of compounds or isolated compounds to function as medicinal remedies or dietary supplements. Phenolic compounds are widely used and include hydroxycinnamic acids, present in a variety of vegetables, fruits and grains. These acids exhibit interesting bioactivities such as antioxidant, antimicrobial, prevention of cardiovascular diseases and immunomodulation. Use of hydroxycinnamic acids in animal production is currently limited but may hold promise in promoting growth. Before this can occur further research is needed on their pharmacokinetics and pharmacodynamics, posology, exposition period and effects, as well as their possible metabolic routes and biotransformation in animal organisms. This review covers inclusion of hydroxycinnamic acids in livestock diets, their pharmacokinetic properties and pharmacodynamics, and findings on their effects in promoting growth and improving meat quality.

Keywords : Hydroxycinnamic acids; Ruminants; Monogastrics; Pharmacokinetic; Pharmacodynamic; Growth promoter.

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