Introduction:

Guillain-Barré syndrome (GBS) is generally considered monophasic, but recurrences occur in a subgroup of patients with a recurrence rate of 1 to 6%. With the advent of the SARS-CoV-2 pandemic, reports of GBS have increased, in addition to recurrent GBS.

Clinical case:

46-year-old male, who six years ago presented GBS associated with Campylobacter jejuni, with ad integrum recovery; in the last year he presented a GBS recurrence, but with a difference of being more severe and with a descending character, unlike from the first episode. On both occasions, he was treated by the same medical team, managed in a similar way, achieving a later recovery in the second episode.

Conclusions:

Although there is still controversy in the literature, recurrent GBS occurs in younger people, and the pictures can be more severe in subsequent episodes.