Abstract

MERINO RIVERA, José Alfonso; TARACENA PACHECO, Santiago; DIAZ GREENE, Enrique Juan  and  RODRIGUEZ WEBER, Federico Leopoldo. Gut microbiota: “the forgotten organ”. Acta méd. Grupo Ángeles [online]. 2021, vol.19, n.1, pp.92-100.  Epub Jan 31, 2022. ISSN 1870-7203.

In the last 10 years, a lot of articles have been published related to the human microbiota, especially in the gut. This ecosystem of microorganisms, as a whole, has a genome broader than human, that gives microbiota the ability to regulate processes that converge in the physiology of immunological pathways and in the pathophysiology of intestinal and extra-intestinal diseases. Applying these new concepts in the clinical, para-clinical and therapeutic evaluation of a patient, today represents a challenge, because factors involved in the formation of the microbiota, in the changes it presents throughout life and the factors that influence in modify and maintain its composition, diversity and metabolism, are highly variable. Some are beyond our control, such as the type of birth, but others not, such as diet, fiber consumption and probiotics, they interfere significantly with modifications to microbiota and subsequently to the general health of the guest. The following review consists in a synthesis of the most relevant functional aspects of the intestinal microbiota, this with the aim to spread the topic and to motivate in new research focused on clinical-therapeutic applications.

Keywords : Microbiota; human microbiome; probiotics; gut.

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