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Acta médica Grupo Ángeles
Print version ISSN 1870-7203
Abstract
GONZALEZ VERGARA, Carolina et al. Correlation of viral load in RT-PCR test for SARS-CoV-2 infection and specific findings in chest computed tomography. Acta méd. Grupo Ángeles [online]. 2020, vol.18, n.4, pp.382-389. Epub June 06, 2022. ISSN 1870-7203. https://doi.org/10.35366/97264.
Of all patients infected with the SARS-CoV-2 virus, 13.8% evolve to a critical illness; for this reason, an early detection of the viral RNA is needed to contain the sources of infection and progression of the disease. The viral load replication has a direct relationship to the progress of tomographic manifestations corresponding to pulmonary damage produced by SARS-CoV-2 infection.
Objective:
To correlate specific tomographic findings of pulmonary damage to the viral load estimation determined by quantitative and qualitative RT-PCR test and to define if there is a relationship at the time of diagnosis of COVID-19 disease.
Material and methods:
Cross-sectional descriptive study at Hospital Ángeles Mocel in Mexico City with an original cohort of 358 patients with a total sample of 74.
Results:
CT was positive in 93%; global average age 50.03, 71.6% male. Mean viral replication 25.5 copies over 40 and moderate qualitative at 55.4%. There is no significant difference for any of the studied variables between each of the tomographic findings and viral load.
Conclusion:
Despite high sensibility proved by CT, it is not yet indicated as a screening tool, and a higher amount of studies are required to establish it as a prognostic factor.
Keywords : SARS; SARS-CoV-2; COVID; RT-PCR; PCR; CT COVID.
