SciELO - Scientific Electronic Library Online

vol.58 issue2A Green Approach to the Production of 2-pyridone Derivatives Promoted by Infrared IrradiationOne-pot Synthesis of Benzo[c]acridine Derivatives Using SBA-Pr-SO3H as Nano Catalyst author indexsubject indexsearch form
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • Have no similar articlesSimilars in SciELO


Journal of the Mexican Chemical Society

Print version ISSN 1870-249X


MALEKI, Behrooz  and  SEDIGH ASHRAFI, Samaneh. "In Situ" Generated "HCl": A Highly Efficient Catalyst for One-Pot Synthesis of 1H -Indazolo [1,2-b]phthalazine-1,6,11-triones and 1H- pyrazolo[1,2-b]phthalazine-5,10-diones under Solvent-Free Conditions. J. Mex. Chem. Soc [online]. 2014, vol.58, n.2, pp.159-167. ISSN 1870-249X.

The rapid and environmental synthetic route to produce 1H-indazolo[1,2-b] phthalazine-1,6,11-triones and 1H-pyrazolo[1,2-b]phthalazine-5,10-diones derivatives have been developed via multi-component and one-pot reactions of various aldehydes, cyclic or acyclic 1,3-diketones with: i) phthalhydrazide or ii) phthalic anhydride-hydrazinium hydroxide using wet 2,4,6-trichlorotriazine (TCT) as catalyst under solvent-free conditions. Simple and mild reaction conditions, the use of a cheap catalyst and easy workup and isolation are notable features of this method.

Keywords : 1H-Indazolo[1,2-b]phthalazine-1,6,11-triones; 1H-pyrazolo[1,2-b]phthalazine-5,10-diones; 2,4,6-trichlorotriazine; 1,3-diketones; phthalhydrazide; aldehydes; solvent-free reactions.

        · abstract in Spanish     · text in English     · English ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License