SciELO - Scientific Electronic Library Online

 
vol.49 issue2Interaction Parameter (Χ); Expansion Factor (ε); Steric Hindrance Factor (σ); and Shielding Function F(ξ); for the System PEA-Organic Solvents by Intrinsic Viscosity MeasurementsThe Solid-State and Solution-State Reassigned Structures of Tagitinin A, a 3,10-Epoxy-Germacrolide from Tithonia diversifolia, and the Interconversion of 3,10-Epoxy-Germacrolide Conformational Families via a Ring-Atom Flip Mechanism author indexsubject indexsearch form
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • Have no similar articlesSimilars in SciELO

Share


Journal of the Mexican Chemical Society

Print version ISSN 1870-249X

Abstract

AMBROZIN, Alessandra R. P. et al. New Pyrone and Quinoline Alkaloid from Almeidea rubra and their Trypanocidal Activity. J. Mex. Chem. Soc [online]. 2005, vol.49, n.2, pp.196-201. ISSN 1870-249X.

The investigation of the ethyl acetate fraction of methanol extract from leaves of Almeidea rubra A. St.-Hil. (Rutaceae) afforded two new compounds 4-methoxy-6-[2-(methylamino)phenyl]-2H-pyran-2-oneand rel-(7R,8R)-8-[(E)-3-hydroxy-3-methyl-1-butenyl]-4,8-dimethoxy-5,6,7,8-tetrahydrofuro[2,3-b]quinoline-7-yl acetate, along with the known compounds arborinine, N-methyl-1-hydroxy-3-methoxyacridone, skimmianine, kokusagine, isodutaduprine, isoskimmianine, and isokokusagine. Their structures were established based on their spectral data, and for the new compounds these data are described herein. Additionally, these compounds were assayed on the tripomastigote forms of Trypanosoma cruzi showing moderate trypanocidal activity.

Keywords : Almeidea rubra; Rutaceae; alkaloids; trypanocidal activity.

        · abstract in Portuguese     · text in English     · English ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License