Abstract

PALOS, Isidro  and  RIVERA, Gildardo. Quinoxaline 1,4-dioxide: a viable option for the development of antitubercular drugs. Rev. mex. cienc. farm [online]. 2015, vol.46, n.2, pp.17-23. ISSN 1870-0195.

Tuberculosis is a major infectious disease in the world, which causes high mortality. The treatment consists of drugs of first and second line; however, its effectiveness is limited by several factors, mainly the presence of resistant and/or multi-drug resistant strains. This work reviews compounds derived from quinoxaline 1,4-dioxide with antimycobacterial activity in in vitro and in vivo models as an option for the development of new drugs against tuberculosis.

Keywords : Tuberculosis; drugs; quinoxaline 1,4-dioxide.

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