Abstract

HERNANDEZ-RODRIGUEZ, Jorge et al. How intrauterine growth restriction due to nutritional stress changes the function of key proteins in brain serotonin metabolism during development. Bol. Med. Hosp. Infant. Mex. [online]. 2021, vol.78, n.6, pp.571-583.  Epub Dec 16, 2021. ISSN 1665-1146.  https://doi.org/10.24875/bmhim.20000334.

This review aimed to describe and comment on how experimental intrauterine nutritional stress in animals produced some changes in tryptophan-5-hydroxylases (TPH) 1 and 2 in the brain and other key proteins such as plasma albumin, and how the intrauterine nutritional stress could produce long-lasting alterations in serotonin function in the brain of human infants.

Keywords : Intrauterine growth restriction; Undernourishment; Serotonin neurons; Tryptophan-5-hydroxylases; Plasma albumin.

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