Abstract

SALGADO-ZAMORA, Héctor; CAMPOS, Ma. Elena; JIMENEZ, Rogelio  and  CERVANTES, Humberto. An Unexpected Condensation Reaction Involving 2-Aminopyridine, DMF and Barbituric Acids. Rev. Soc. Quím. Méx [online]. 2004, vol.48, n.4, pp.246-249. ISSN 0583-7693.

In this investigation the reaction of 2-aminopyridine with barbituric acid derivatives was explored. It was found that the reaction of 2-aminopyridine with 1,3-dimetylbarbituric and barbituric acids yielded an unexpected condensation product whose formation resembles a Mannich-type reaction. While the reaction with 5,5-dibromobarbituric acid yielded the corresponding 5-bromo-2-aminopyridine.

Keywords : 2-aminopyridine; barbituric acid derivatives; condensation reactions.

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