Abstract

VAZQUEZ-MORALES, Horacio; JAIME-CORDOVA, Arturo  and  VARGAS-SANCHEZ, Verónica. Malignant hyperthermia in a patient undergoing Madden type radical mastectomy. Rev. mex. anestesiol. [online]. 2023, vol.46, n.3, pp.208-211.  Epub Sep 08, 2023. ISSN 0484-7903.  https://doi.org/10.35366/111078.

The objective of the present is to present the anesthetic management that occurred before a critical event malignant hyperthermia HM) in an electively scheduled Madden radical mastectomy and which was managed with what was available at that time for not having the drug specific (dantrolene) for this type of event HM. Breast cancer is a complex disease, being the leading cause of death in women worldwide, with 70% occurring in developed countries. Mexico is at an intermediate level, being a health problem with a tendency to rise due to the aging of the population. population and higher prevalence of risk factors. Malignant hyperthermia (MH) is an anesthetic-triggered pharmacogenetic disorder that triggers a massive accumulation of calcium in the sarcoplasm, leading to accelerated metabolism and increased skeletal muscle contractile activity. Leading to a hypermetabolic state showing an increase in body temperature, leading to significant sequelae and high mortality. It was a 40-year-old female with no relevant history for anesthetic procedures, being managed with balanced general anesthesia at 60 minutes present data clinicians that they suggested malignant hyperthermia, being managed. With the available means, obtaining a favorable result from the point of view of morbidity and mortality.

Keywords : malignant hyperthermia; dantrolene; Madden mastectomy; sevoflurane.

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