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Ginecología y obstetricia de México

Print version ISSN 0300-9041

Abstract

GALVAN-LUNA, Adriana; PENA-VEGA, Cynthia Jazmín; MEDINA-HERNANDEZ, Elba Onelida  and  ZAVALA-BARRIOS, Berenice. Preeclampsia as a risk factor for chronic renal failure and survival years. Ginecol. obstet. Méx. [online]. 2021, vol.89, n.6, pp.444-452.  Epub Feb 28, 2022. ISSN 0300-9041.  https://doi.org/10.24245/gom.v89i6.4664.

OBJECTIVE:

To establish survival years in patients with a history of preeclampsia and subsequent chronic disease.

MATERIALS AND METHODS:

Retrospective, descriptive, comparative and analytical study carried out between March 2018 and March 2019 in patients attended at the Hospital General de México Dr. Eduardo Liceaga in follow-up due to pregnancy and diagnosis of chronic kidney disease and history of preeclampsia in any of the pregnancies.

RESULTS:

We evaluated 66 patients with preeclampsia, average age 23.7 years, and mean age 37.9 years at diagnosis of chronic renal failure. 60.6% had systemic arterial hypertension following the preeclampsia event (OR of 3.34; 95%CI: 0.94-11.95) and onset of chronic renal failure. Kaplan-Meier survival in association with chronic renal failure following preeclampsia was 9.9 years (95%CI: 7.8 -1.8).

CONCLUSIONS:

Although the relationship between a history of preeclampsia and chronic kidney disease has been demonstrated, studies are still limited. Kaplan-Meier survival shows that at least 50% of patients with CKD had preeclampsia and were diagnosed with CKD 9.9 years later. Based on this study and similar outcomes in international evidence, it can be concluded that multidisciplinary care, prioritizing prevention and including preeclampsia as a risk factor for CKD, is essential.

Keywords : Pre-Eclampsia; Pregnancy; Chronic kidney disease; Chronic renal failure; Risk factors; Chronic disease; Follow-Up studies.

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