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Ginecología y obstetricia de México

Print version ISSN 0300-9041

Abstract

GUZMAN-SOLIS, Martha Cecilia et al. Obstetric outcomes in pregnant women with chronic kidney disease and associated factors. Ginecol. obstet. Méx. [online]. 2020, vol.88, n.4, pp.230-243.  Epub Aug 30, 2021. ISSN 0300-9041.  https://doi.org/10.24245/gom.v88i4.3325.

OBJECTIVE:

To know the factors associated with fetal, maternal and renal outcomes in known pregnant women with chronic kidney disease.

MATERIALS AND METHODS:

An observational, prospective study at the IMSS Hospital of Gynecobstetrics No. 4 from 2016 to 2018 of pregnant women with chronic kidney disease with biochemical parameters (creatinine, urea) and obstetric outcomes; Incomplete cases were excluded. For the type of population, non-parametric statistics were used with median (central tendency), interquartile range (dispersion), for the comparison of means, a student&apos;s “t” was used, with a significance of p < 0.05 and Kruskal Wallis. To establish risk, a bivariate analysis is performed. SPSS 25 statistical program.

RESULTS:

The obstetric results obtained were: 16/48 of the women with preeclampsia, caesarean section was the most common resolution in 32/48 cases. In relation to newborns, 41 survived, 22/41 with prematurity, 19/41 were full term, 29/41 newborns without complications. There was an elevation of 0.28 mg/dL creatinine and a decrease in the glomerular filtration rate of 9.67 mL/min.

CONCLUSIONS:

4 factors were identified. Pulmonary maturation and chronic-degenerative diseases represented a risk for prematurity; Two influential factors for the termination of pregnancy were: not taking preeclampsia and having no hospitalization and/or infection events. chronic kidney disease directly influences both maternal and fetal adverse outcomes, and pregnancy also has an influence on greater renal impairment.

Keywords : Pregnant Women; Chronic Kidney Disease; Creatinine Urea; Glomerular Filtration Rate; Cesarean Section; Pre-Eclampsia; Renal Insufficiency; Infant, Low Birth Weight.

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