BACKGROUND:

Churg-Strauss syndrome is an ANCA-associated vasculitis that mainly affects small vessels. Asthma, fever, eosinophilia and small vessel vasculitis are the main clinical characteristics. The most commonly observed complication is preterm delivery. Other complications are fetal loss, fetal growth restriction and more often cesarean delivery.

CLINICAL CASE:

A 38-year-old woman, first pregnancy, with previous diagnosis of Churg-Strauss Syndrome. Woman is in remission for 4 years, maintaining treatment with glucocorticoid. Pregnancy advance without complications, with normal laboratory data (negative ANCA), without severe asthmatic crisis. She only refers to episodes of mild bronchial asthma and well controlled with described medication and allergic rhinitis. Ultrasound identifies low fetal weight, without signals of fetal growth restriction. A cesarean section was performed at 38+6 weeks of pregnancy for breech presentation, after failure of external cephalic version. Neonate has a 15th percentile of weight, an APGAR of 10/10 and a umbilical artery pH of 7.27. Newborn does not require reanimation or NICU admission. Puerperium was normal.

CONCLUSIONS:

Diagnosis prior to pregnancy is very important for the prognosis of pregnancy. It allows to choose the perfect moment for pregnancy start (remission, absence of mother organic complications, negative antibodies) and to control and reduce the complications occurrence.

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