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Ginecología y obstetricia de México
Print version ISSN 0300-9041
Abstract
ROQUE-FERNANDEZ, María Ángeles et al. Elevated progesterone level at oocyte retrieval and IVF outcome. Ginecol. obstet. Méx. [online]. 2019, vol.87, n.11, pp.740-746. Epub Aug 20, 2021. ISSN 0300-9041. https://doi.org/10.24245/gom.v87i11.3089.
OBJECTIVE:
To investigate the relationship between serum progesterone level on the day of oocyte retrieval and pregnancy outcomes in patients undergoing IVF.
MATERIALS AND METHODS:
Prospective cohort study of IVF-ICSI cycles, with long or antagonistic agonist protocol and with fresh embryo transfer on day 2-3. We proposed a serum progesterone level on p90 on day of oocyte retrieval. The main outcome analysed are biochemichal and clinical pregnancy and first trimester miscarriage.
RESULTS:
400 cycles of IVF-ICSI were studied, with long agonist protocol (n = 41) or antagonist (n = 359) and with fresh embryo transfer on day 2-3. Pregnancy rate was similar in both groups (41 vs 40.2%) and clinical pregnancy rate was lower (30.8 vs 33.5%), but it wasn’t statically significance. There was more miscarriage in elevation progesterone group (25.7 vs 43.8%), but it wasn´t statiscally significance.
CONCLUSION:
Progesterone elevation on oocyte retrieval are not associated with the IVF outcome, but there is a trend to lower clinical pregnancy and more miscarriages.
Keywords : Progesterone; Oocyte retrieval; Pregnancy outcome; Pregnancy rate.
