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Ginecología y obstetricia de México

Print version ISSN 0300-9041

Abstract

VILLALOBOS-EQUIHUA, Carolina; RUIZ-MARINES, Daniel; ORTIZ-VERDIN, Maira Denisy  and  MARTINEZ-HERNANDEZ, Francisco Javier. Ewing's sarcoma as a cause of abnormal uterine bleeding. Report of a case. Ginecol. obstet. Méx. [online]. 2019, vol.87, n.9, pp.610-614.  Epub Aug 20, 2021. ISSN 0300-9041.  https://doi.org/10.24245/gom.v87i9.3126.

BACKGROUND:

Primitive neuroectodermal tumors originate from mesenchymal progenitor cells and are part of various neoplasms, known as the Ewing family tumors. Its expression in the female reproductive system (mainly in the ovary and the uterine body) is an exceptional event.

CLINICAL CASE:

A 13-year-old patient, who went to the Gynecological Emergency Department of the Hospital de la Mujer de Morelia, Michoacán, with hypermenorrhea of 5 months of evolution, colic pain in the hypogastrium, without improvement despite the use of analgesics; loss of 3 kg in 1 month and affectation to the general state of health. A physical examination was found: abdomen with a tumor of 10 x 10 cm in the pelvic hollow. It was decided to perform exploratory laparotomy with total abdominal hysterectomy, right oophorectomy and left salpingectomy. The pathology study reported a small round and blue cell tumor that affected the bottom of the vaginal sac and cervix. The immunohistochemical study confirmed the diagnosis of Ewing's sarcoma. The patient was sent to the Oncology state center to receive chemotherapy and radiotherapy; however, it was lost in the follow-up.

CONCLUSIONS:

Abnormal uterine bleeding is one of the most frequent reasons for gynecological consultation in adolescents, which associated with some neoplasm is an exceptional event. Ewing sarcomas constitute less than 1% of malignant lesions of the cervix. Despite its low prevalence and few cases reported in the literature, it should be considered in the differential diagnosis of gynecological tumors.

Keywords : Primitive neuroectodermal tumor; Mesenchymal progenitor cells; Hypermenorrhea; Ewing sarcoma; Adolescents.

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