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Ginecología y obstetricia de México
Print version ISSN 0300-9041
Abstract
HINOJOSA-RODRIGUEZ, KA et al. Prevalence of thyroid autoimmunity in subfertile women. Ginecol. obstet. Méx. [online]. 2017, vol.85, n.10, pp.694-704. ISSN 0300-9041. https://doi.org/10.24245/gom.v85i10.1577.
OBJECTIVE:
To estimate the prevalence of autoimmune thyroid disease in subfertile patients who come to the Human Reproduction service of the National Institute of Perinatology Isidro Espinosa de los Reyes, Mexico city.
MATERIAL AND METHODS:
A retrospective, cross-sectional, observational, ambispective study evaluating 18- to 43-year-old women from the INPer "Isidro Espinosa de los Reyes" human reproduction service with a thyroid profile determination with anti-thyroid antibodies in The first consultation of infertility.
RESULTS:
The prevalence of TEE in the population of infertile women is 19%. 48% have seropositivity for Ac-TPO, 32% for Ac-tiroglobulina plus Ac-TPO and the remaining 20% only for Ac-tiroglobulina. A prevalence of clinical hypothyroidism of 8% and subclinical of 48% was observed in the group of patients with ATE. The mean TSH for women with ATE was 4.6 μUI/L. Women with isolated euthyroid ETA represent 8.3% of the population and have a high rate of previous spontaneous abortions (45.5%) as well as failure in assisted reproduction techniques (70%).
CONCLUSION:
Determination of thyroid autoimmunity should be routinely performed in the female population.
Keywords : Autoimmune thyroid disease; Autoimmune thyroid disease isolated euthyroid; Clinical hypothyroidism; Subclinical hypothyroidism; Clinical pregnancy; Miscarriage; Death; failed assisted reproduction techniques.