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Revista mexicana de cardiología
Print version ISSN 0188-2198
Abstract
BETANCUR, Laura et al. Association of epicardial adipose tissue with incidence, severity and recurrences of atrial fibrillation: results of a systematic review. Rev. Mex. Cardiol [online]. 2018, vol.29, n.1, pp.55-66. ISSN 0188-2198.
Introduction:
Atrial fibrillation is the most prevalent arrhythmia in clinical practice. Evidence has recently shown a relationship between epicardial adipose tissue and atrial fibrillation, which may be stronger than that for traditional obesity markers.
Objective:
To analyse the available evidence associating adipose epicardial tissue with incidence, severity and recurrences of atrial fibrillation.
Methods:
A systematic search in PubMed, EBSCO, Cochrane, SciELO and LILACS databases for observational studies published in the last 10 years, evaluating the association between atrial fibrillation and epicardial adipose tissue was undertaken. All articles were evaluated by two authors and differences were solved by consensus.
Results:
After having screened and evaluated articles for quality, 15 were selected for the qualitative synthesis. All studies reported a statistically significant association between total fat and periatrial epicardial adipose tissue and the presence of atrial fibrillation, which persisted after adjustment of covariates. The evidence was not uniform regarding arrhythmia severity. Periatrial epicardial fat was significantly higher in patients who had a recurrent disease.
Conclusion:
the presence of epicardial adipose tissue (total and periatrial) is significantly associated with atrial fibrillation and arrhythmia recurrence.
Keywords : Atrial fibrillation; epicardial adipose tissue; epicardial fat; pericardial fat.