Abstract

CARRILLO-ESPER, Raúl  and  PEREZ CALATAYUD, Ángel Augusto. Ultra-protective lung ventilation in acute respiratory failure, a new concept. Rev. Asoc. Mex. Med. Crít. Ter. Intensiva [online]. 2015, vol.29, n.4, pp.234-239. ISSN 0187-8433.

Acute respiratory distress syndrome (ARDS) is a severe and frequent affection in critically ill patients. Damage of the lung endothelial barrier induce from inflammation which results in a capillary leak and surfactant dysfunction thereby varying degrees of alveolar consolidation may occur. In order to reduce lung injury from mechanical ventilation, different strategies have been created. The accepted strategy with strong scientific evidence is lung protective ventilation. In recent years the presence of CO₂ removers without the use of extracorporeal arterio-venous pumps have been developed and tested for clinical use, it's use allows the removal of CO₂ with moderate improvement in oxygenation. A strategy with ultralow tidal volume in mechanical ventilation (3 mL/kg of predicted weight) in combination with CO₂ removers devices could reduce CO₂ extraction of lung injury associated with ventilation compared to the current protector management, yet to be determined whether this strategy will improve the survival of patients with ARDS.

Keywords : Acute respiratory distress syndrome; mechanical ventilation; ultralow tidal volume.

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