Abstract

DURAN CRUZ, MAURICIO; LUJAN CASTILLA, POMPONIO JOSÉ  and  SANCHEZ MARIN, GABRIEL ALEJANDRO. AMILOIDOSIS LARÍNGEA. REPORTE DE UN CASO TRATADO EXITOSAMENTE CON RADIOTERAPIA EXTERNA. Rev. Inst. Nal. Enf. Resp. Mex. [online]. 2004, vol.17, n.3, pp.198-203. ISSN 0187-7585.

Laryngeal amyloidosis is an uncommon disease accounting for 0.68% of benign tumors of the larynx. It can present as a nodular tumor or diffuse subepithelial deposition forming a mass and causing hoarseness, dysphagia or even airway obstruction. Treatment has historically focused on debridement, laser ablation, stent placement and in some cases colchicine, melphalan and prednisone. We present a case of laryngeal amyloidosis persistent to management with laser ablation and melphalan/prednisone, successfully managed with external beam radiation therapy. Fourteen months after a moderate radiation dose, the patient remained without symptomatic or image data of disease. The literature concerning the role of radiation therapy in the treatment of laryngeal amyloidosis is reviewed.

Keywords : Amyloidosis; larynx; radiotherapy.