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Perinatología y reproducción humana
On-line version ISSN 2524-1710Print version ISSN 0187-5337
Abstract
OSTIA-GARZA, Patricia J.; LUNA-RIOS, Erika and PLAZA-BENHUMEA, Lautaro. Exencephaly: prenatal diagnosis and case report. Perinatol. Reprod. Hum. [online]. 2022, vol.36, n.1, pp.25-29. Epub Sep 30, 2022. ISSN 2524-1710. https://doi.org/10.24875/per.20000024.
Exencephaly is a type of cephalic disorder, where the brain is located outside of the skull. Congenital malformations constitute a public health problem in Mexico, affecting approximately 2-6% of newborns. Central nervous system malformations are the second most frequent malformations in the population of Mexico. As with most congenital malformations, the etiology of central nervous system anomalies is multifactorial, resulting from interactions among genetic, infectious, environmental, racial, physical and chemical factors, and deficiency or alteration of folic acid metabolism. We also review the embryology of this entity, with emphasis of the importance of folic acid intake at the stage of central nervous system embryogenesis, and also the importance of the prenatal care.
Keywords : Exencephaly; Central nervous system malformations; Prenatal care; Paliative care.