Abstract

MARTINEZ-RUIZ, EE.; PAZ-MANIFACIO, S.; SANCHEZ-DIAZ, JS.  and  GONZALEZ-DE LA CRUZ, E.. Rhabdomyolysis due to hypokalemia: an atypical manifestation of Conn’s syndrome. Med. interna Méx. [online]. 2017, vol.33, n.6, pp.826-834. ISSN 0186-4866.  https://doi.org/10.24245/mim.v33i6.1417.

Rhabdomyolysis is a condition with a broad spectrum of presentation that can range from mild asymptomatic disease to fatal complications due to electrolyte imbalance, arrhythmias and/or acute renal injury. We report the case of a 35-year-old woman, hypertensive, who was admitted for muscle weakness following a gastrointestinal condition. Biochemically with severe hypokalemia, elevated creatinekinase, conserved renal function, hypocalcemia and metabolic alkalosis. Their comprehensive evaluation culminated in the diagnosis of primary hyperaldosteronism secondary to an aldosterone-producing adenoma which was surgically removed without complications. The presentation of Conn’s syndrome with hypokalemia rhabdomyolysis is exceptional since most cases are diagnosed with normokalemia or mild hypokalemia from the secondary hypertension protocol. A high level of suspicion and integral evaluation are necessary to arrive at the correct diagnosis.

Keywords : rhabdomyolysis; hypokalemia; hypocalcemia; primary hyperaldosteronism; Conn’s syndrome; aldosterone-producing adenoma.

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