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Medicina interna de México
Print version ISSN 0186-4866
Abstract
CARRILLO-ESPER, R.; CARRILLO-CORDOVA, D.M.; CARRILLO-CORDOVA, C.A. and BRACHO-OLVERA, HR. Sleep disorders in the critically ill patient. An event of great impact and little taken into account. Med. interna Méx. [online]. 2017, vol.33, n.5, pp.618-633. ISSN 0186-4866. https://doi.org/10.24245/mim.v33i5.1558.
Sleep is important for good outcome and recovery in critically ill patients. Sleep disturbances affect commonly critically ill patients and are associated with impair of immune system, anabolic and regenerative processes, neurophysiologic organization, cognitive dysfunction, delirium, prolonged Intensive Care Unit stay and mortality. The critically ill present pathologic sleep patterns characterized by abnormal circadian rhythm, high arousal and awakening index, reduced slow wave sleep and rapid eye movement sleep. Melatonin is a promissory prophylactic or therapeutic agent in the management of sleep disturbances. The aim of this paper is to review current concepts related to sleep disturbances in the critically ill, their clinical impact, prevention and the new therapeutic alternatives.
Keywords : sleep; sleep disturbances; melatonin; critically ill patient.