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Salud Pública de México
Print version ISSN 0036-3634
Abstract
CUPUL-UICAB, Lea Aurora et al. Covid-19 during pregnancy: a rapid review and meta-analysis. Salud pública Méx [online]. 2021, vol.63, n.2, pp.242-252. Epub Feb 27, 2023. ISSN 0036-3634. https://doi.org/10.21149/11810.
Objective:
To summarize the scientific evidence of adverse health effects of Covid-19 during pregnancy.
Materials and methods
We conducted a Cochrane rapid review. Meta-analysis of proportions and odds ratios (OR) were performed.
Results:
Frequent maternal events included invasive mechanic ventilation and admission to the intensive care unit (ICU); pregnancy complications were fetal distress and premature rupture of membranes; common comorbidities were obesity and asthma. Deliveries by cesarean section (C-section) due to Covid-19 were frequent (51%). The most frequent neonatal outcomes were low birthweight and prematurity; we identified cases of SARS-CoV-2 positive neonates (14%). Pregnant women with Covid-19 were more likely to deliver by C-section (pooled OR=6.7) and prematurely (pooled OR=2.9); neonates were more likely to be admitted to the neonatal ICU (pooled OR=5.9).
Conclusion:
The available evidence on Covid-19 during pregnancy is limited. Therefore, we cannot disregard adverse health effects on the mother-child pair, particularly those related to C-sections and premature deliveries.
Keywords : Covid-19; meta-analysis; neonates; pregnancy; pregnant women; SARS-CoV-2.