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Neumología y cirugía de tórax
Print version ISSN 0028-3746
Abstract
MONTERO-URENA, Raúl Enrique et al. Thoracic air leak syndrome due to graft-versus-host disease after allogeneic bone marrow transplantation. Neumol. cir. torax [online]. 2021, vol.80, n.2, pp.118-121. Epub Nov 01, 2021. ISSN 0028-3746. https://doi.org/10.35366/100993.
Introduction:
Currently, hematopoietic stem cell transplant (HSCT) is a treatment for hematological neoplasms. Graft-versus-host disease (GVHD) is a complication of HSCT, pulmonary involvements are frequent, among them is thoracic air leak syndrome (SFAT).
Clinical case:
22-year-old male with acute myeloblastic leukemia (AML), post allogeneic HSCT (HPT). In those who are admitted for recurrent spontaneous pneumothorax, infectious processes are ruled out and biopsies are taken with reports compatible with GVHD. Treatment was by endopleural catheter and bilateral pleurodesis, with adequate resolution of the condition after the latter.
Conclusion:
SFAT is a rare and late non-infectious lung complication of HPT, characterized by spontaneous pneumothorax. Which is associated with a poor forecast.
Keywords : Thoracic air leak syndrome; graft versus host disease; allogeneic bone marrow transplantation; anti-Ro52.
