Background:

Prader-Willi syndrome (PWS) is a genetic disorder with multiple risk factors to develop sleep disorders of breathing (SDB). The aim of the study is to describe the polysomnographic findings of children with PWS treated at the Respiratory Sleep Disorders Clinic INER.

Material and methods:

Clinical records were reviewed from January 01, 2005 to December 31, 2015. Children under 18 years of age with genetic diagnosis of PWS studied by nocturnal polysomnography were included. Polysomnograms were eliminated with total sleep time less than 4 hours and/or sleep efficiency less than 70%.

Results:

Four children were identified, mostly in adolescence, all with obesity and multiple comorbidities. Three patients met the criterion of some SDB, 1 had hypoventilation during sleep, 1 hypoventilation during sleep + obstructive apnea and another with central apnea.

Conclusions:

The SDB are highly frequent among patients with PWS, the most frequent disorder was hypoventilation syndrome during sleep.