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Gaceta médica de México
On-line version ISSN 2696-1288Print version ISSN 0016-3813
Abstract
CARRANZA-LIRA, Sebastián et al. Relation of vitamin D blood concentration with muscle mass and cognitive function in postmenopausal women. Gac. Méd. Méx [online]. 2021, vol.157, n.5, pp.503-511. Epub Dec 13, 2021. ISSN 2696-1288. https://doi.org/10.24875/gmm.21000421.
Introduction:
Low levels of vitamin D have been associated with muscle mass loss and cognitive function alteration.
Objective:
To find out the relationship of vitamin D blood levels with muscle mass and cognitive function in postmenopausal women.
Materials and methods:
Ninety-nine postmenopausal women aged ≥ 50 years were studied. Calf circumference, and tricipital, bicipital, subscapular and suprailiac skinfolds were measured. Arm muscle area, bone-free arm muscle area, and total muscle mass were calculated. The short physical performance battery (SPPB) was performed, and the sarcopenia rapid diagnostic questionnaire (SARC-F), as well as the Mini Mental State Examination (MMSE) were applied. A blood sample was taken to measure vitamin D blood concentration. For statistical analysis, Mann-Whitney's U-test and Spearman's correlation analysis were used.
Results:
It was found that, the older the age, the higher the vitamin D levels, as well as higher SARC-F score. Vitamin D levels were negatively correlated with grip strength SPP and the MMSE total score. There was a negative correlation between vitamin D levels and MMSE global score.
Conclusions:
Vitamin D did not have a positive influence on muscle mass. A better MMSE performance was observed in those with lower vitamin D levels.
Keywords : Sarcopenia; Muscular strength; Post-menopause; Vitamin D; Body fat; Cognition.