SciELO - Scientific Electronic Library Online

vol.142 issue5Tagliacozzi: not just a plastic surgeonPolymorphism analysis of G199A, Ncol in ANK1 and Memphis I in SLC4A1 genes in Mexican healthy individuals and subjects affected with hereditary spherocytosis author indexsubject indexsearch form
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • Have no similar articlesSimilars in SciELO


Gaceta médica de México

Print version ISSN 0016-3813


PRADO-MONTES DE OCA, Ernesto. Human defensin: prophilaxis and therapy against HIV?. Gac. Méd. Méx [online]. 2006, vol.142, n.5, pp.431-433. ISSN 0016-3813.

Human defensins are endogenous antimicrobial peptides with prophylactic and therapeutic potential against HIV. The ability of defensins to bind the HIV envelope could be exploited to design topic agents that block viral entry into exposed mucosa. Additionally, their capacity to inhibit viral replication, complement system activation, dendritic and memory T cells chemoattraction, together with peptide engineering could bring about new and better antiretroviral drugs. Clinical trials could be demonstrated the efficacy of defensins against HIV in clinical practice.

Keywords : HIV; human defensins; antimicrobial peptides; therapy; prophylaxis.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License