Abstract

CALDERON-GARCIDUENAS, Ana Laura et al. Clinicopathologic Characteristics and Distibution of Number of Autopsies of Patient Death Due to Coccidioidomycosis at a Referral Hospital in Northeastern México. Gac. Méd. Méx [online]. 2004, vol.140, n.4, pp.399-404. ISSN 2696-1288.

Aims: 1. To describe clinical and pathologic characteristics of patients with coccidioidomycosis (CM) who died from 1983-2000 at a hospital in northeastern Mexico, and 2, to know distribution of number of deaths due to CM per year and month. Methods: from 4598 autopsies, 31 cases of CM were selected. Clinical chart and autopsy protocols were examined. Distribution of cases was analyzed by contingence table and Kolmogorov-Smirnov tests. Results: there were 10 women and 21 men (aged 4 months to 60 years). In women, pregnancy was present in 40%ofcases. In men, chronic renal failure (CRF) (38%) and AIDS (19%) were the pathologic conditions most frequently observed. Variation in distribution of cases throughout 18 years was not observed (p > 0.05). Conclusions: mortality due to CM was 0.67% and variation in number of deaths was not found. In this endemic area, CM must be included in differential diagnosis of patients with risk factors such as pregnancy, CRF, and AIDS, especially if associated with pneumonia with miliary pattern or septicemia with splenomegaly.

Keywords : Coccidioidomycosis; autopsy; Mexico; mortality.

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