Abstract

DOELLO-GONZALEZ, Kevin; AMEZCUA-HERNANDEZ, Víctor  and  VALDIVIA-BAUTISTA, Javier. Ectopic ACTH secretion and hyperaldosteronism as an unusual paraneoplastic syndrome in a patient with metastatic small cell lung cancer. Gac. mex. oncol. [online]. 2021, vol.20, suppl.1, pp.151-153.  Epub Aug 22, 2022. ISSN 2565-005X.  https://doi.org/10.24875/j.gamo.20000070.

Small cell lung cancer is usually associated with paraneoplastic syndromes due to hormonal secretion, the most frequent, the syndrome of inappropriate antidiuretic hormone secretion. A case of a hyperaldosteronism and ectopic secretion of adrenocorticotropic hormone associated with small cell lung cancer is presented. A 59-year-old patient was studied for a constitutional syndrome diagnosing a metastatic small cell lung cancer. In the course of the oncological process, he manifests a clinic of hypertension, hypernatremia and hypokalemia. After a hormonal study he is diagnosed with a paraneoplastic hyperaldosteronism that is controlled with antihypertensives and antialdosteronics. The patient finally died due to liver progression of his tumor disease.

Keywords : Small cell lung cancer; Hyperaldosteronism; ACTH.

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