Case report:

A 53-year-old female with a deceased-donor kidney transplant who was receiving quadruple sequential immunosuppressive therapy, with a delayed graft function in her immediate postoperative period, and no need for dialysis. Two months later, the patient was hospitalized due to sudden eye pain, low grade fever and myalgia. A nuclear magnetic resonance showed space occupying injuries in the CNS, suggesting an infectious process and diffuse graft pyelonephritis, requiring a transplantectomy. The patient died 24 hours after the surgery despite the antifungal therapy. The kidney tissue culture revealed Scedosporium apiospermun growth.

Relevance:

The case highlights the importance of knowing and being able to manage infections in a timely manner, given the growing number of transplanted patients with immunosuppressive therapy.

Clinical implications:

The Scedosporium apiospermun is an emerging, ubiquitous, and opportunistic fungus that causes systemic infections in immunocompromised patients that may produce up to 90% of mortality, and local infections that requires surgical debridement and long-term antifungal treatment with voriconazole for at least 3 months.

Conclusions:

Despite this type of infection not being frequently seen, it demands a quick differential diagnosis and an appropriate treatment, given the potential mortality and morbidity outcomes.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )