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Revista mexicana de urología
On-line version ISSN 2007-4085Print version ISSN 0185-4542
Abstract
ALMEIDA-MAGANA, R; AGUILAR-DAVIDOV, B; PRIEGO-NINO, A and CASTILLO-CANTO, C. Advanced collecting duct carcinoma in three patients. Rev. mex. urol. [online]. 2018, vol.78, n.1, pp.67-72. Epub Dec 16, 2021. ISSN 2007-4085. https://doi.org/10.24245/revmexurol.v78i1.1541.
Background:
Collecting duct carcinoma is an extremely rare type of renal cell carcinoma and accounts for 0.5 to 3% of malignant kidney cancers. It is an aggressive, rapidly invasive disease that progresses to early metastasis.
Clinical case:
Three cases of advanced-stage collecting duct carcinoma confirmed through histologic study are reported herein. The clinical characteristics of the patients were reviewed retrospectively. All the patients had a history of smoking, were symptomatic at the time of diagnosis, and presented with advanced-stage disease. The three patients underwent radical nephrectomy and all died before the end of two postoperative months: 2 of the deaths were due to postoperative complications and 1 from early disease progression.
Conclusions:
Cytoreductive nephrectomy may be a source of morbidity and mortality. Larger case series are required to define its role in the treatment of collecting duct carcinoma.
Keywords : Collecting duct carcinoma; Radical nephrectomy; Kidney cancer; Postoperative complications.