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Acta médica Grupo Ángeles

Print version ISSN 1870-7203

Abstract

CARRILLO SANCHEZ, Angélica Maricela et al. Incidence of the location of fractures in the multiple myeloma in the Regional Hospital “Gral. Ignacio Zaragoza” ISSSTE. Acta méd. Grupo Ángeles [online]. 2021, vol.19, n.4, pp.497-500.  Epub Aug 01, 2022. ISSN 1870-7203.  https://doi.org/10.35366/102534.

Multiple myeloma is a hematological neoplasm derived from alterations in B lymphoid cells characterized by skeletal abnormalities called multiple myeloma bone disease.

Objective:

Determine the location of fractures in patients with multiple myeloma at the Regional Hospital “Gral. Ignacio Zaragoza” from 2016 to 2019.

Material and methods:

Retrospective study, we reviewed the radiological clinical records of patients diagnosed with multiple myeloma in the period from January 2016 to December 2019.

Results:

We included 33 patients with multiple myeloma. Three patients (9.1%) presented a fracture with characteristics of a neoplastic process and subsequent diagnosis of multiple myeloma. Other patients had symptoms of multiple myeloma bone disease: low back pain 42.4% (n = 14), generalized bone pain 15.2% (n = 5). In 24 patients, we documented a fracture associated with multiple myeloma: spine 39.4% (n = 13), humerus 12.1% (n = 4), hip 9.1% (n = 3), appendicular skeleton 9.1% (n = 3) and femur 3% (n = 1).

Conclusion:

24 patients (78.7%) were diagnosed with a fracture associated with multiple myeloma, being more frequent in the spine, humerus, and hip.

Keywords : Multiple myeloma; multiple myeloma bone disease; fracture.

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