Abstract

CARREON-SANCHEZ, Rodolfo et al. Study of ethanolic extract of Eryngium heterophyllum (herb frog): To make sure its hypoglycemic and anti-inflammatory activity. Rev. mex. cienc. farm [online]. 2013, vol.44, n.2, pp.41-45. ISSN 1870-0195.

The aim of this study was to assess an acute toxicity assay, as well as the alleged anti-inflammatory and hypoglycemiant activities of an ethanolic extract of Eryngium heterophyllum. Serum levels of Nitrites and ceruloplasmin were quantified too. Results. Ethanolic extract not showed any visible signs of intoxication, nor lost weight in animals after 7 days of treatment. This extract no showed any anti-inflammatory activity, in the acute and chronic models assessed. The ethanolic extract had not hypoglycemiant activity and no differences were observed in the ceruloplasmin levels or nitrite concentration, in daily administration during a week of this extract, in the statistical analysis also showed no differences between the treatment groups. Conclusion. This ethanolic extract of Eryngium heterophyllum should not be recommended for use in diabetes or inflammatory processes such as rheumatoid arthritis.

Keywords : Eryngium heterophyllum (grass toad); anti-inflammatory; hypoglycemic treatment.

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