Abstract

GOMEZ SANDOVAL, Jenny; TALAMAS ROHANA, Patricia  and  AGUIRRE GARCIA, Magdalena. Proteínas fosfatasas de parásitos: más allá de una función. Rev. educ. bioquím [online]. 2014, vol.33, n.1, pp.4-12. ISSN 1665-1995.

Protein phosphatases are enzymes that dephosphorylate proteins in tyrosine and serine/threonine residues, and are involved in various cellular processes, whose functions have been best characterized in eukaryotic cells. However, in the last two decades these enzymes have been identified and characterized in infectious microorganisms such as parasites. It has been found that certain parasite phosphatases maintain conserved functions similar to those of higher eukaryotes, whereas other phosphatases have unique structural and/or functional characteristics, which make them candidates for drug development or as diagnostic markers. This paper encompasses the knowledge generated to date, about the role of these enzymes in parasites of medical and veterinary importance.

Keywords : Protein phosphatase; parasite; pathogen.

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